Cas 100523-84-0 - A Valuable Thiophene Derivative For Synthesis And Materials Applications

5-Bromothiophene-3-carboxylic acid CAS: 100523-84-0 is an important thiophene derivative featuring an aromatic thiophene ring, a carboxylic group, and a bromine substituent. This unique structural combination provides multiple reactive sites, making it highly versatile in organic synthesis and functional material development. The compound usually appears as a light-colored solid with good stability and selective reactivity. Synthetic Reactivity The reactivity of 5-Bromothiophene-3-carboxylic acid mainly comes from its bromine substituent and carboxyl group: Coupling reactions: The bromine atom enables Pd-catalyzed Suzuki, Stille, and Sonogashira couplings to synthesize polysubstituted thiophene derivatives. Condensation/Esterification: The carboxyl group can undergo condensation, esterification, or acyl chloride formation to yield diverse derivatives for pharmaceuticals and functional monomers. Structural modification: Further substitution reactions can be carried out to tune the electronic properties of thiophene compounds for various R&D purposes. Applications Pharmaceutical chemistry: Serves as a key intermediate in synthesizing thiophene-containing drug molecules, with potential in anti-inflammatory, antimicrobial, and CNS-related drug candidates. Materials science: Thiophene derivatives are essential building blocks for organic semiconductors, OLEDs, and photovoltaic materials. Fine chemicals: With dual functional groups, it is a flexible raw material for designing new functional molecules and high-performance monomers. UCHEM Advantage UCHEM supplies high-purity 5-Bromothiophene-3-carboxylic acid (CAS: 100523-84-0) with ready stock to ensure fast delivery for both research and industrial needs. For researchers and enterprises seeking high-quality thiophene intermediates, UCHEM is your trusted partner.