Cas: 3001-72-7 - High-Performance Non-Nucleophilic Base From Uchem

1,5-Diazabicyclo[4.3.0]non-5-ene CAS: 3001-72-7, commonly known as DBN, is a bicyclic amidine base widely used in organic synthesis and process chemistry. Owing to its strong basicity and low nucleophilicity, DBN is particularly effective in reactions where proton abstraction is required without competing nucleophilic side reactions. DBN is frequently applied in elimination reactions, cyclizations, condensations, and transition-metal-catalyzed transformations. Its rigid bicyclic structure enhances basic strength while maintaining good solubility in common organic solvents, making it suitable for both laboratory-scale synthesis and industrial processes. Typical Applications ?Strong base for elimination and dehydrohalogenation reactions ?Cyclization and condensation processes ?Base component in coupling and rearrangement reactions ?Process chemistry and scale-up synthesis UCHEM supplies high-purity 1,5-Diazabicyclo[4.3.0]non-5-ene with reliable batch-to-batch consistency. The product is suitable for use in fine chemical synthesis, pharmaceutical intermediate production, and process development. Flexible supply options and technical documentation are available to support scale-up and long-term projects.